Interplay between Helicobacter pylori and host gene polymorphisms in inducing oxidative DNA damage in the gastric mucosa.

@article{Izzotti2007InterplayBH,
  title={Interplay between Helicobacter pylori and host gene polymorphisms in inducing oxidative DNA damage in the gastric mucosa.},
  author={Alberto Izzotti and S De Flora and Cristina Cartiglia and Bianca Maria Are and Mariagrazia Longobardi and Anna Camoirano and Ida Mura and Maria Pina Dore and Antonio Mario Scanu and Paolo Cossu Rocca and Alessandro Maida and Andrea Fausto Piana},
  journal={Carcinogenesis},
  year={2007},
  volume={28 4},
  pages={892-8}
}
Infection by Helicobacter pylori is the most important risk factor for gastric cancer. However, only a small fraction of colonized individuals, representing at least half of the world's population, develop this malignancy. In order to shed light on host-microbial interactions, gastric mucosa biopsies were collected from 119 patients suffering from dyspeptic symptoms. 8-Hydroxy-2'-deoxyguanosine (8-oxo-dG) levels in the gastric mucosa were increased in carriers of H.pylori, detected either by… CONTINUE READING

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Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer

  • D. R. Scott, E. A. Marcus, D. L. Weeks, G. Sachs
  • Cancer Res .
  • 2003

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