Interplay among membrane properties, protein properties and operating conditions on protein fouling during normal-flow microfiltration

@article{Loh2009InterplayAM,
  title={Interplay among membrane properties, protein properties and operating conditions on protein fouling during normal-flow microfiltration},
  author={ShyTyug Loh and U. Beuscher and Tarun Poddar and Andrew J. Porter and J. Wingard and S. Husson and S. R. Wickramasinghe},
  journal={Journal of Membrane Science},
  year={2009},
  volume={332},
  pages={93-103}
}
  • ShyTyug Loh, U. Beuscher, +4 authors S. R. Wickramasinghe
  • Published 2009
  • Chemistry
  • Journal of Membrane Science
    • Abstract Normal-flow filtration is used frequently in the biopharmaceutical industry for applications such as sterile filtration of fermentation media, buffers and product proteins. Though the membrane pores are much larger than the product protein, protein fouling of the membrane often leads to a decrease in permeate flux at constant feed pressure. Normal-flow microfiltration experiments were conducted using polytetrafluoroethylene (PTFE) and polyvinylidene fluoride (PVDF) base membranes, PTFE… CONTINUE READING
    View via Publisher
    46 Citations
    Highly Influential Citations
    1
    Background Citations
    9
    Methods Citations
    5
    46 Citations
    Citation Type

    Citation Type

    Fouling of microfiltration membranes by organic polymer coagulants and flocculants: controlling factors and mechanisms.
    • 47
    Forward osmosis membrane performance during simulated wastewater reclamation : fouling mechanisms and fouling layer properties
    • 15
    Prefiltration to suppress protein fouling of microfiltration membranes
    • 8
    The Influence of Ion Identity and Ionic Strength on Membrane Biofouling of a Binary Protein Solution
    The effects of buffer condition on the fouling behavior of MVM virus filtration of an Fc‐fusion protein
    • 1
    Ultrafiltration of humic acid solutions through unmodified and surface functionalized low-fouling polyethersulfone membranes – Effects of feed properties, molecular weight cut-off and membrane chemistry on fouling behavior and cleanability
    • 64
    Performance of Thin-Layer Hydrogel Polyethersulfone Composite Membranes during Dead-End Ultrafiltration of Various Protein Solutions
    • 23
    Understanding virus filtration membrane performance
    • 51
    Novel membrane surface modification to enhance anti-oil fouling property for membrane distillation application
    • 143
    Assessment of fouling-resistant membranes for additive-free treatment of high-strength wastewaters
    • 11

    References

    SHOWING 1-10 OF 26 REFERENCES
    Membrane fouling during microfiltration of protein mixtures
    • 141
    Protein Fouling of Track-Etched Polycarbonate Microfiltration Membranes
    • 247
    Effect of membrane morphology on the initial rate of protein fouling during microfiltration
    • 178
    Protein fouling of surface-modified polymeric microfiltration membranes
    • 137
    Protein fouling in microfiltration: deposition mechanism as a function of pressure for different pH.
    • 61
    Properties of microfiltration membranes: Flux loss during constant pressure permeation of bovine serum albumin
    • 158
    Mechanisms for BSA fouling during microfiltration
    • 206
    Intermolecular Electrostatic Interactions and Their Effect on Flux and Protein Deposition during Protein Filtration
    • 93
    A Combined Pore Blockage and Cake Filtration Model for Protein Fouling during Microfiltration.
    • Ho, Zydney
    • Chemistry, Medicine
    • Journal of colloid and interface science
    • 2000
    • 533
    Compaction and permeability effects with virus filtration membranes
    • 66