Interplasmid transposition demonstrates piggyBac mobility in vertebrate species

  title={Interplasmid transposition demonstrates piggyBac mobility in vertebrate species},
  author={Neil F. Lobo and Tresa S. Fraser and John A. Adams and Malcolm J. Fraser},
The piggyBac transposon is an extremely versatile helper-dependent vector for gene transfer and germ line transformation in a wide range of invertebrate species. Analyses of genome sequencing databases have identified piggyBac homologues among several sequenced animal genomes, including the human genome. In this report we demonstrate that this insect transposon is capable of transposition in primate cells and embryos of the zebrafish, Danio rerio. piggyBac mobility was demonstrated using an… CONTINUE READING
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