Interphotoreceptor retinoid-binding protein. Gene characterization, protein repeat structure, and its evolution.

@article{Borst1989InterphotoreceptorRP,
  title={Interphotoreceptor retinoid-binding protein. Gene characterization, protein repeat structure, and its evolution.},
  author={Diane E Borst and T Michael Redmond and John E. Elser and M. C. Arufe Gonda and Barbara N Wiggert and Gerald J. Chader and John M. Nickerson},
  journal={The Journal of biological chemistry},
  year={1989},
  volume={264 2},
  pages={1115-23}
}
The gene for bovine interphotoreceptor retinoid-binding protein (IRBP) has been cloned, and its nucleotide sequence has been determined. The IRBP gene is about 11.6 kilobase pairs (kb) and contains four exons and three introns. It transcribed into a large mRNA of approximately 6.4 kb and translated into a large protein of 145,000 daltons. To prove the identity of the genomic clone, we determined the protein sequence of several tryptic and cyanogen bromide fragments of purified bovine IRBP… CONTINUE READING