Interphase cytogenetics: a new tool for the study of genetic changes in brain tumors.

@article{Arnoldus1992InterphaseCA,
  title={Interphase cytogenetics: a new tool for the study of genetic changes in brain tumors.},
  author={E. P. J. Arnoldus and Lex Wolters and Joan H C Voormolen and Sjoerd G. van Duinen and Anton K. Raap and M P Van der Ploeg and A. C. Boudewijn Peters},
  journal={Journal of neurosurgery},
  year={1992},
  volume={76 6},
  pages={997-1003}
}
Interphase cytogenetics is the application of nonradioactive in situ hybridization with chromosome-specific DNA probes to interphase nuclei. In this study, interphase cytogenetics was used to investigate 66 primary brain tumors (33 gliomas, 30 meningiomas, and three medulloblastomas) for numerical chromosomal aberrations of chromosomes 1, 6, 7, 10, 11, 17, 18, X, and Y. Of the 33 gliomas (17 astrocytomas grades II, III, and IV, five oligoastrocytomas, seven oligodendrogliomas, and four… CONTINUE READING

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