Interphase FISH in plasma cell dyscrasia: increase in abnormality detection with plasma cell enrichment.


Historically, cytogenetic studies of plasma cell neoplasms have been hampered by the fact that terminally differentiated plasma cells do not proliferate well in vitro. Although the use of interphase FISH (iFISH) has greatly improved the ability to detect cytogenetic abnormalities, cases with low numbers of neoplastic cells often do not demonstrate… (More)
DOI: 10.1016/j.cancergencyto.2008.11.007


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