Interorgan ammonia and amino acid metabolism in metabolically stable patients with cirrhosis and a TIPSS.

@article{Damink2002InterorganAA,
  title={Interorgan ammonia and amino acid metabolism in metabolically stable patients with cirrhosis and a TIPSS.},
  author={Steven W. M. Olde Damink and Rajiv Jalan and Doris N. Redhead and P C Hayes and Nicolaas E P Deutz and Peter B. Soeters},
  journal={Hepatology},
  year={2002},
  volume={36 5},
  pages={1163-71}
}
Ammonia is central to the pathogenesis of hepatic encephalopathy. This study was designed to determine the quantitative dynamics of ammonia metabolism in patients with cirrhosis and previous treatment with a transjugular intrahepatic portosystemic stent shunt (TIPSS). We studied 24 patients with cirrhosis who underwent TIPSS portography. Blood was sampled and blood flows were measured across portal drained viscera, leg, kidney, and liver, and arteriovenous differences across the spleen and the… CONTINUE READING

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