Internodal myelination during development quantitated using X-ray diffraction.

  title={Internodal myelination during development quantitated using X-ray diffraction.},
  author={Deepika S. Agrawal and Rachel Hawk and Robin L. Avila and Hideyo Inouye and Daniel A. Kirschner},
  journal={Journal of structural biology},
  volume={168 3},
Characterizing the formation, accretion, and stability of myelin during development, maturation, and senescence is important for better understanding critical periods in the function of the nervous system in normal growth and following environmental insult or genetic mutation. Although there are numerous studies on the ultrastructural, biochemical, and genetic aspects of myelin development and maturation, few have used X-ray diffraction (XRD), which can rapidly provide unique metrics about… CONTINUE READING


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