Interneuronal signalling is involved in induction of collateral sprouting of nociceptive axons.

@article{Bajrovic2002InterneuronalSI,
  title={Interneuronal signalling is involved in induction of collateral sprouting of nociceptive axons.},
  author={Fajko Fejzo Bajrovic and Uro{\vs} Kova{\vc}i{\vc} and M Pavcnik and Janez Sketelj},
  journal={Neuroscience},
  year={2002},
  volume={111 3},
  pages={587-96}
}
Collateral sprouting of cutaneous nociceptive axons into the adjacent denervated skin critically depends on the nerve growth factor, presumably originating from the degenerated neural pathways and denervated skin. We hypothesised that the degenerated neural pathways are necessary, but not sufficient, to induce collateral sprouting of nociceptive axons, and, in addition, that the interaction between the injured and non-injured neurones within a dorsal root ganglion can trigger sprouting of… CONTINUE READING