Interneuron dysfunction in psychiatric disorders

  title={Interneuron dysfunction in psychiatric disorders},
  author={Oscar Mar{\'i}n},
  journal={Nature Reviews Neuroscience},
  • O. Marín
  • Published 1 February 2012
  • Psychology, Medicine
  • Nature Reviews Neuroscience
Schizophrenia, autism and intellectual disabilities are best understood as spectrums of diseases that have broad sets of causes. However, it is becoming evident that these conditions also have overlapping phenotypes and genetics, which is suggestive of common deficits. In this context, the idea that the disruption of inhibitory circuits might be responsible for some of the clinical features of these disorders is gaining support. Recent studies in animal models demonstrate that the molecular… 
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