Interneuron diversity series: containing the detonation--feedforward inhibition in the CA3 hippocampus.

Abstract

Feedforward inhibitory circuits are involved both in the suppression of excitability and timing of action potential generation in principal cells. In the CA3 hippocampus, a single mossy fiber from a dentate gyrus granule cell forms giant boutons with multiple release sites, which are capable of detonating CA3 principal cells. By contrast, mossy fiber… (More)

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