Interneuron and pyramidal cell interplay during in vitro seizure-like events.

  title={Interneuron and pyramidal cell interplay during in vitro seizure-like events.},
  author={Jokubas Ziburkus and John R. Cressman and Ernest Barreto and Steven J. Schiff},
  journal={Journal of neurophysiology},
  volume={95 6},
Excitatory and inhibitory (EI) interactions shape network activity. However, little is known about the EI interactions in pathological conditions such as epilepsy. To investigate EI interactions during seizure-like events (SLEs), we performed simultaneous dual and triple whole cell and extracellular recordings in pyramidal cells and oriens interneurons in rat hippocampal CA1. We describe a novel pattern of interleaving EI activity during spontaneous in vitro SLEs generated by the potassium… CONTINUE READING
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Comparable GABAergic mechanisms of hippocampal seizure - like activity in post - tetanic and low - Mg 2  conditions

  • Y Fujiwara-Tsukamoto, Y Isomura, M Takada
  • J Neurophysiol
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Inhibitory and excitatory interplay : neuronal conductance measures during in vitro seizures

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1 Excerpt

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