International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels

@article{Catterall2005InternationalUO,
  title={International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels},
  author={W. Catterall and A. Goldin and S. G. Waxman},
  journal={Pharmacological Reviews},
  year={2005},
  volume={57},
  pages={397 - 409}
}
  • W. Catterall, A. Goldin, S. G. Waxman
  • Published 2005
  • Medicine
  • Pharmacological Reviews
  • The family of voltage-gated sodium channels initiates action potentials in all types of excitable cells. Nine members of the voltage-gated sodium channel family have been characterized in mammals, and a 10th member has been recognized as a related protein. These distinct sodium channels have similar structural and functional properties, but they initiate action potentials in different cell types and have distinct regulatory and pharmacological properties. This article presents the molecular… CONTINUE READING
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    References

    SHOWING 1-10 OF 396 REFERENCES
    Structure and function of voltage-gated ion channels
    • 750
    • PDF
    Pharmacology, Structure and Function of Cardiac L-Type Ca2+ Channels
    • J. Striessnig
    • Biology, Medicine
    • Cellular Physiology and Biochemistry
    • 1999
    • 193
    • Highly Influential
    Calcium channelopathies: voltage-gated calcium channels.
    • 49
    • PDF
    Structure and function of voltage-dependent sodium channels: comparison of brain II and cardiac isoforms.
    • 296
    Molecular mechanisms of neurotoxin action on voltage-gated sodium channels.
    • 615
    Voltage-dependent calcium channels: from structure to function.
    • 340
    Resurgence of sodium channel research.
    • A. Goldin
    • Medicine, Biology
    • Annual review of physiology
    • 2001
    • 668
    • PDF
    Voltage-gated sodium channels as therapeutic targets.
    • 182
    • Highly Influential
    From Ionic Currents to Molecular Mechanisms The Structure and Function of Voltage-Gated Sodium Channels
    • 1,848
    • PDF
    Nomenclature of Voltage-Gated Calcium Channels
    • 823