International Union of Basic and Clinical Pharmacology. LXXXIV: Leukotriene Receptor Nomenclature, Distribution, and Pathophysiological Functions

  title={International Union of Basic and Clinical Pharmacology. LXXXIV: Leukotriene Receptor Nomenclature, Distribution, and Pathophysiological Functions},
  author={M. B{\"a}ck and S. Dahl{\'e}n and J. Drazen and J. Evans and C. Serhan and T. Shimizu and T. Yokomizo and G. Rovati},
  journal={Pharmacological Reviews},
  pages={539 - 584}
  • M. Bäck, S. Dahlén, +5 authors G. Rovati
  • Published 2011
  • Biology, Medicine
  • Pharmacological Reviews
  • The seven-transmembrane G protein-coupled receptors activated by leukotrienes are divided into two subclasses based on their ligand specificity for either leukotriene B4 or the cysteinyl leukotrienes (LTC4, LTD4, and LTE4). These receptors have been designated BLT and CysLT receptors, respectively, and a subdivision into BLT1 and BLT2 receptors and CysLT1 and CysLT2 receptors has been established. However, recent findings have also indicated the existence of putative additional leukotriene… CONTINUE READING
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