International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature

@inproceedings{Gnther2018InternationalUO,
  title={International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature},
  author={Thomas G{\"u}nther and Giovanni Tulipano and Pascal Dournaud and Corinne Bousquet and Zsolt Csaba and H J Kreienkamp and Amelie Lupp and M{\'a}rta Korbonits and Justo Pastor Casta{\~n}o and Harald Wester and Michael Culler and Shlomo Melmed and Sebastian Schulz},
  booktitle={Pharmacological reviews},
  year={2018}
}
Somatostatin, also known as somatotropin-release inhibitory factor, is a cyclopeptide that exerts potent inhibitory actions on hormone secretion and neuronal excitability. Its physiologic functions are mediated by five G protein-coupled receptors (GPCRs) called somatostatin receptor (SST)1-5. These five receptors share common structural features and signaling mechanisms but differ in their cellular and subcellular localization and mode of regulation. SST2 and SST5 receptors have evolved as… CONTINUE READING
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Publications referenced by this paper.
SHOWING 1-10 OF 780 REFERENCES

Somatostatin receptors, in IUPHAR/BPS Guide to Pharmacology

S Schulz, C Bosquet, +7 authors A Schonbrunn
  • 2017
VIEW 30 EXCERPTS
HIGHLY INFLUENTIAL

A (2015a) Somatostatin receptors in bronchopulmonary neuroendocrine neoplasms: new diagnostic, prognostic, and therapeutic markers

D Kaemmerer, E Specht, +4 authors Lupp
  • J Clin Endocrinol Metab
  • 2015
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

A (2015b) Inverse expression of somatostatin and CXCR4 chemokine receptors in gastroenteropancreatic neuroendocrine neoplasms of different malignancy

D Kaemmerer, T Träger, +5 authors Lupp
  • Oncotarget
  • 2015
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL