International Fanconi Anemia Registry: relation of clinical symptoms to diepoxybutane sensitivity

  title={International Fanconi Anemia Registry: relation of clinical symptoms to diepoxybutane sensitivity},
  author={Arleen D. Auerbach and Andr{\'e} Rogatko and Traute Marianne Schroeder-Kurth},
  volume={73 2},
Fanconi anemia (FA) is characterized clinically by a progressive pancytopenia, diverse congenital abnormalities and increased predisposition to malignancy. Although a variable phenotype makes accurate diagnosis on the basis of clinical manifestations difficult in some patients, study of cellular sensitivity to the clastogenic effect of DNA cross-linking agents such as diepoxybutane (DEB) has been used to facilitate the diagnosis. Data from DEB-induced chromosomal breakage studies of 328… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 94 extracted citations


Publications referenced by this paper.
Showing 1-10 of 36 references

Carcinogen - induced chromosome breakage in chromosome instability syndromes

  • AD Auerbach, Wolman
  • Curr Probl Dermatol
  • 1987

Cyclosporin A therapy of aplastic anemia and pure red cell aplasias

  • E Gluckman, A Devergie, +4 authors J Bernard
  • Blood
  • 1987

Multicenter trial of antithymocyte globulin ( ATG ; Upjohn ) in acute , chronic , and moderate aplastic anemia and other bone marrow failure states

  • E Leonard, E Raefsky, AW Nienhuis, P Griffith, N Young
  • Blood
  • 1987

Similar Papers

Loading similar papers…