• Corpus ID: 13115245

International Congress on Hormonal Steroids and Hormones and Cancer The role of vitamin D and retinoids in controlling prostate cancer progression

@inproceedings{Peehl2003InternationalCO,
  title={International Congress on Hormonal Steroids and Hormones and Cancer The role of vitamin D and retinoids in controlling prostate cancer progression},
  author={Donna M. Peehl and David Feldman},
  year={2003}
}
Prostate cancer is a leading cause of cancer-related deaths in many countries. Premalignant lesions and invasive cancer occur more frequently in the prostate than in any organ other than the skin. Yet, the incidence of clinically detected prostate cancer is much lower than the histopathological incidence. The slow growth of prostate cancer and the low incidence of clinically manifest disease in some geographical locations or racial/ethnic groups suggest that prostate cancer can be controlled… 
2 Citations
Pre-clinical evidence and clinical translation of benign prostatic hyperplasia treatment by the vitamin D receptor agonist BXL-628 (Elocalcitol)
TLDR
The capacity of VDR agonists to treat benign prostatic hyperplasia (BPH), a complex syndrome characterized by a static component related to prostate overgrowth, a dynamic component responsible for urinary irritative symptoms, and a possible inflammatory component, is analysed.

References

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TLDR
The epidemiological evidence supporting a role for 1,25D deficiency in the genesis of prostatic cancer is reviewed, the effects that this hormone has on benign and malignant prostatic epithelial cells in culture, the mechanisms through which it produces these effects and the potential clinical utility are reviewed.
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TLDR
If treatment with vitamin D would be a viable management alternative for the patient described in the case study is reviewed to determine if it is useful both in the prevention and treatment of prostate cancer.
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TLDR
It is projected that prostate cancer will become the leading cause of cancer and cancer death in men in the United States and for that matter, in the rest of the world as well.
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
It is hypothesized that Vitamin (Hormone) D deficiency may underlie the major risks for prostate cancer, including age, Black race, and northern latitudes, which are associated with decreased synthesis of Vitamin D.
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