International Commission for Protection Against Environmental Mutagens and Carcinogens. Genetic risk extrapolation from animal data to human disease. A Taskgroup Report. No. 00105.

Abstract

This report describes a model for producing quantitative genetic risk assessments for human populations. The model is patterned after current methods used in cancer risk analysis. The risk to humans is expressed as the number of additional dominant genetic diseases added to the existing genetic burden, in the offspring of the exposed individuals.

Cite this paper

@article{Favor1978InternationalCF, title={International Commission for Protection Against Environmental Mutagens and Carcinogens. Genetic risk extrapolation from animal data to human disease. A Taskgroup Report. No. 00105.}, author={Judy Favor and Danielle M Layton and Gregor {\vS}ega and John S. Wassom and Joe Burkhart and George R. Douglas and Kerry L. Dearfield and David J. Brusick}, journal={Mutation research}, year={1978}, volume={76 1}, pages={85-112} }