International Atomic Energy Agency Randomized Phase III Study of Radiation Therapy in Elderly and/or Frail Patients With Newly Diagnosed Glioblastoma Multiforme.

@article{Roa2015InternationalAE,
  title={International Atomic Energy Agency Randomized Phase III Study of Radiation Therapy in Elderly and/or Frail Patients With Newly Diagnosed Glioblastoma Multiforme.},
  author={Wilson H.-Y. Roa and L Kepka and Narendra Kumar and Valery Sinaika and Juliana Matiello and Darejan Lomidze and Dalenda Hentati and Douglas Guedes de Castro and Katarzyna Dyttus-Cebulok and Suzanne C. Drodge and Sunita Ghosh and Branislav Jeremic and Eduardo Rosenblatt and Elena F Fidarova},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2015},
  volume={33 35},
  pages={
          4145-50
        }
}
PURPOSE The optimal radiotherapy regimen for elderly and/or frail patients with newly diagnosed glioblastoma remains to be established. This study compared two radiotherapy regimens on the outcome of these patients. PATIENTS AND METHODS Between 2010 and 2013, 98 patients (frail = age ≥ 50 years and Karnofsky performance status [KPS] of 50% to 70%; elderly and frail = age ≥ 65 years and KPS of 50% to 70%; elderly = age ≥ 65 years and KPS of 80% to 100%) were prospectively randomly assigned to… CONTINUE READING
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