Internalization of components of the host cell plasma membrane during infection by Trypanosoma cruzi.

@article{Carvalho1999InternalizationOC,
  title={Internalization of components of the host cell plasma membrane during infection by Trypanosoma cruzi.},
  author={T{\'e}cia Maria Ulisses de Carvalho and Wanderley de Souza and Elaine Soares Coimbra},
  journal={Memorias do Instituto Oswaldo Cruz},
  year={1999},
  volume={94 Suppl 1},
  pages={143-7}
}
Epimastigote and trypomastigote forms of Trypanosoma cruzi attach to the macrophage surface and are internalized with the formation of a membrane bounded vacuole, known as the parasitophorous vacuole (PV). In order to determine if components of the host cell membrane are internalized during formation of the PV we labeled the macrophage surface with fluorescent probes for proteins, lipids and sialic acid residues and then allowed the labeled cells to interact with the parasites. The interaction… CONTINUE READING

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