Internalization of Chlamydia by dendritic cells and stimulation of Chlamydia-specific T cells.

@article{Ojcius1998InternalizationOC,
  title={Internalization of Chlamydia by dendritic cells and stimulation of Chlamydia-specific T cells.},
  author={David M. Ojcius and Y Bravo de Alba and Jean M. Kanellopoulos and Ray A. Hawkins and Kathleen Kelly and Roger G. Rank and Alice Dautry-Varsat},
  journal={Journal of immunology},
  year={1998},
  volume={160 3},
  pages={1297-303}
}
Chlamydia species are the causative agents of trachoma, various forms of pneumonia, and the most common sexually transmitted diseases. Although the infection cycle has been extensively characterized in epithelial cells, where the Chlamydia entry-vacuoles avoid fusion with host-cell lysosomes, the cellular immune response has received less attention. Moreover, despite the abundant presence of dendritic cells (DC) in the sites of infection, the interaction between Chlamydia and DC has never been… CONTINUE READING

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