Internalization of Aeromonas hydrophila by fish epithelial cells can be inhibited with a tyrosine kinase inhibitor.

@article{Tan1998InternalizationOA,
  title={Internalization of Aeromonas hydrophila by fish epithelial cells can be inhibited with a tyrosine kinase inhibitor.},
  author={Eunice L P Tan and Kathleen Low and Weng Sie Wong and Ka Yin Leung},
  journal={Microbiology},
  year={1998},
  volume={144 ( Pt 2)},
  pages={
          299-307
        }
}
Aeromonas hydrophila is a Gram-negative bacterium that is pathogenic in fish, causing motile aeromonad septicaemia. It can enter (invade) fish cells, and survive as an intracellular parasite. The host-pathogen interaction and signal transduction pathway were studied by screening signal transduction inhibitors using carp epithelial cells and a virulent strain of the bacterium, PPD134/91. Genistein, a tyrosine kinase inhibitor, postponed internalization of A. hydrophila into host cells… CONTINUE READING

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