Internalin of Listeria monocytogenes with an intact leucine-rich repeat region is sufficient to promote internalization.

@article{Lecuit1997InternalinOL,
  title={Internalin of Listeria monocytogenes with an intact leucine-rich repeat region is sufficient to promote internalization.},
  author={Marc Lecuit and H{\'e}l{\`e}ne Ohayon and Laurence Braun and J{\'e}r{\^o}me Mengaud and Pascale Cossart},
  journal={Infection and immunity},
  year={1997},
  volume={65 12},
  pages={5309-19}
}
Listeria monocytogenes can use two different surface proteins, internalin (InlA) and InlB, to invade mammalian cells. The exact role of these invasiveness factors in vivo remains to be determined. In cultured cells, InlA is necessary to promote Listeria entry into human epithelial cells, such as Caco-2 cells, whereas InlB is necessary to promote Listeria internalization in several other cell types, including hepatocytes, fibroblasts, and epithelioid cells, such as Vero, HeLa, CHO, or Hep-2… CONTINUE READING

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