Internal transcriptional regulatory elements in HIV-1 and other retroviruses.

Abstract

The transcriptional regulation of retroviruses plays an important role in their pathogenesis. Cis-acting elements have been identified in the long terminal repeat (LTR) at the 5' extremity of the integrated provirus. These elements determine the rate and the site of transcription initiation and consist of arrays of binding sites for transcription factors… (More)

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