Internal standard method for the measurement of choline and acetylcholine by capillary electrophoresis with electrochemical detection.

Abstract

An internal standard method has been developed for the determination of the neurotransmitter acetylcholine and/or its metabolic precursor choline. This approach couples the high separation efficiency of capillary electrophoresis with the sensitivity and selectivity of electrochemical detection at an enzyme-modified electrode. Indirect electrochemical… (More)

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Cite this paper

@article{Wise2002InternalSM, title={Internal standard method for the measurement of choline and acetylcholine by capillary electrophoresis with electrochemical detection.}, author={Dana Diane Wise and Tatyana V Barkhimer and Pierre-Alexandre Brault and Jon R Kirchhoff and William S. Messer and Richard A. Hudson}, journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences}, year={2002}, volume={775 1}, pages={49-56} }