Internal pilot design for balanced repeated measures.


Repeated measures are common in clinical trials and epidemiological studies. Designing studies with repeated measures requires reasonably accurate specifications of the variances and correlations to select an appropriate sample size. Underspecifying the variances leads to a sample size that is inadequate to detect a meaningful scientific difference, while… (More)
DOI: 10.1002/sim.7524


Cite this paper

@article{Zhang2017InternalPD, title={Internal pilot design for balanced repeated measures.}, author={Xinrui Zhang and Keith E. Muller and Maureen Michels Goodenow and Yueh-Yun Chi}, journal={Statistics in medicine}, year={2017} }