Internal motions in deoxyribonucleic acid II.

  title={Internal motions in deoxyribonucleic acid II.},
  author={Michael E. Hogan and Oleg Jardetzky},
  volume={19 15},
We have measured the 1H, 31P, and 13C NMR parameters of monodisperse deoxyribonucleic acid (DMA) fragments 260 and 140 base pairs long as a function of temperature and solvent viscosity. On the basis of these measurements, we calculate that within a rodlike DNA helix, the base planes, the deoxyribose sugar, and the sugar-phosphate backbone all experience large fast internal motions. The best fit of the data to a two-state model for internal motion specifies for the internal motions the… CONTINUE READING