Internal lamin structures within G1 nuclei of human dermal fibroblasts.

  title={Internal lamin structures within G1 nuclei of human dermal fibroblasts.},
  author={Joanna M Bridger and Ian R. Kill and MINNIE K. O'FARRELL and Christopher J. Hutchison},
  journal={Journal of cell science},
  volume={104 ( Pt 2)},
The nuclear lamina is a mesh-like network of fibres subjacent to the inner nuclear membrane that is believed to be involved in the specific spatial reorganisation of chromatin after mitosis. To determine how the lamina might be involved in chromatin reorganisation, we have performed indirect immunofluorescence studies on quiescent and proliferating human dermal fibroblasts (HDF). Two monoclonal antibodies recognising human lamins A and C and three different fixation methods were employed. In… CONTINUE READING

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