Internal anal sphincter achalasia in children: clinical characteristics and treatment with Clostridium botulinum toxin.

OBJECTIVES To describe the clinical characteristics of children with internal anal sphincter (IAS) achalasia and to evaluate the benefit of intrasphincteric injection of Clostridium botulinum toxin. METHODS Retrospective review of the medical records of 20 patients (8 male, mean 5.8 +/- 4.2 years) with severe chronic constipation and IAS achalasia. Each… CONTINUE READING