Intermolecular interaction studies of winter flounder antifreeze protein reveal the existence of thermally accessible binding state.

The physical nature underlying intermolecular interactions between two rod-like winter flounder antifreeze protein (AFP) molecules and their implication for the mechanism of antifreeze function are examined in this work using molecular dynamics simulations, augmented with free energy calculations employing a continuum solvation model. The energetics for… CONTINUE READING