Intermittent transdermal nitroglycerin therapy. Decreased anginal threshold during the nitrate-free interval.

@article{Parker1995IntermittentTN,
  title={Intermittent transdermal nitroglycerin therapy. Decreased anginal threshold during the nitrate-free interval.},
  author={John D Parker and Anne B Parker and Bernice Farrell and John Orval Parker},
  journal={Circulation},
  year={1995},
  volume={91 4},
  pages={973-8}
}
BACKGROUND Intermittent transdermal nitroglycerin therapy is effective in the treatment of stable angina and prevents the development of tolerance. Previous investigations have suggested that removal of nitroglycerin patches may be associated with a decrease in anginal threshold. This study examines the effect of nitroglycerin patch removal on anginal… CONTINUE READING