Intermittent simulated moving bed chromatography: 2. Separation of Tröger's base enantiomers.

@article{Katsuo2010IntermittentSM,
  title={Intermittent simulated moving bed chromatography: 2. Separation of Tr{\"o}ger's base enantiomers.},
  author={Shigeharu Katsuo and Marco Mazzotti},
  journal={Journal of chromatography. A},
  year={2010},
  volume={1217 18},
  pages={3067-75}
}
The intermittent simulated moving bed (I-SMB) process is a modification of the conventional SMB process that has been recently analyzed theoretically. Here, we present a comparative analysis of the two processes, each operated in a six column 1-2-2-1 configuration (one column in sections 1 and 4 and two columns in sections 2 and 3) and in a four-column 1-1-1-1 configuration. Experiments are carried out on a properly modified laboratory unit to separate racemic mixtures of the enantiomers of Tr… CONTINUE READING

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