Intermittent preventive treatment in infants as a means of malaria control: a randomized, double-blind, placebo-controlled trial in northern Ghana.

@article{Mockenhaupt2007IntermittentPT,
  title={Intermittent preventive treatment in infants as a means of malaria control: a randomized, double-blind, placebo-controlled trial in northern Ghana.},
  author={Frank P Mockenhaupt and Klaus Reither and Philipp Zanger and Felix Roepcke and Ina Danquah and Eiman Adel Hasby Saad and Peter Ziniel and Stephen Y Dzisi and Marc Frempong and Patrick Agana-Nsiire and Felicia Amoo-Sakyi and Rowland N. Otchwemah and Jakob Peter Cramer and Sylvester D. Anemana and Ekkehart Dietz and Ulrich Bienzle},
  journal={Antimicrobial agents and chemotherapy},
  year={2007},
  volume={51 9},
  pages={
          3273-81
        }
}
Morbidity and mortality from malaria remain unacceptably high among young children in sub-Saharan Africa. Intermittent preventive treatment in infancy (IPTi) involves the administration of antimalarials alongside routine vaccinations and might be an option in malaria control. In an area of intense, perennial malaria transmission in northern Ghana, 1,200 children received IPTi with sulfadoxine-pyrimethamine or placebo at approximately 3, 9, and 15 months of age. Children were followed up until… CONTINUE READING
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