Intermittent parathyroid hormone fails to stimulate osseointegration in diabetic rats.

@article{Kuchler2011IntermittentPH,
  title={Intermittent parathyroid hormone fails to stimulate osseointegration in diabetic rats.},
  author={Ulrike Kuchler and Tina Spilka and Katharina Baron and Stefan Tangl and Georg Watzek and Reinhard Gruber},
  journal={Clinical oral implants research},
  year={2011},
  volume={22 5},
  pages={518-23}
}
OBJECTIVES Diabetes is considered a risk factor in the osseointegration of dental implants, which suggests that these patients might benefit from anabolic therapies. Preclinical studies, including investigations by this research group, revealed that intermittent administration of parathyroid hormone (PTH) stimulates bone formation on the surface of titanium implants under physiological conditions. However, the anabolic effect of PTH on osseointegration under the hyperglycemic condition of… CONTINUE READING