Intermittent hypoxia has organ-specific effects on oxidative stress.


Obstructive sleep apnea is characterized by upper airway collapse, leading to intermittent hypoxia (IH). It has been postulated that IH-induced oxidative stress may contribute to several chronic diseases associated with obstructive sleep apnea. We hypothesize that IH induces systemic oxidative stress by upregulating NADPH oxidase, a superoxide-generating… (More)
DOI: 10.1152/ajpregu.90346.2008

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