Intermittent hypoxia and plasticity of respiratory chemoreflexes in metamorphic bullfrog tadpoles.

@article{Simard2003IntermittentHA,
  title={Intermittent hypoxia and plasticity of respiratory chemoreflexes in metamorphic bullfrog tadpoles.},
  author={Edith Simard and Genevi{\`e}ve Tr{\'e}panier and Jacques Larochelle and Richard Kinkead},
  journal={Respiratory physiology & neurobiology},
  year={2003},
  volume={135 1},
  pages={59-72}
}
We tested the hypothesis that intermittent hypoxia elicits plasticity in respiratory chemoreflexes in bullfrog tadpoles. Metamorphic tadpoles (Taylor-Kollros stages XVI-XX) were subjected to intermittent hypoxia (PW(O(2))=45 Torr; 12 h/day) or constant normoxia (PW(O(2))=156 Torr) for 2 weeks before ventilatory responses to hypoxia and hypercarbia were measured. Buccal pressure changes were used to quantify the frequency and amplitude of movements associated with gill and lung ventilation… CONTINUE READING

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