Intermittent access to 20% ethanol induces high ethanol consumption in Long-Evans and Wistar rats.

@article{Simms2008IntermittentAT,
  title={Intermittent access to 20% ethanol induces high ethanol consumption in Long-Evans and Wistar rats.},
  author={Jeffrey A. Simms and Pia Steensland and Brian Medina and Kenneth E Abernathy and L Judson Chandler and R. Todd Wise and Selena E Bartlett},
  journal={Alcoholism, clinical and experimental research},
  year={2008},
  volume={32 10},
  pages={
          1816-23
        }
}
BACKGROUND There has been some difficulty getting standard laboratory rats to voluntarily consume large amounts of ethanol without the use of initiation procedures. It has previously been shown that standard laboratory rats will voluntarily consume high levels of ethanol if given intermittent-access to 20% ethanol in a 2-bottle-choice setting [Wise, Psychopharmacologia 29 (1973), 203]. In this study, we have further characterized this drinking model. METHODS Ethanol-naïve Long-Evans rats were… CONTINUE READING
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