Intermittent Versus Continuous Androgen Deprivation Therapy in Patients with Relapsing or Locally Advanced Prostate Cancer: A Phase 3b Randomised Study (ICELAND).

@article{Schulman2016IntermittentVC,
  title={Intermittent Versus Continuous Androgen Deprivation Therapy in Patients with Relapsing or Locally Advanced Prostate Cancer: A Phase 3b Randomised Study (ICELAND).},
  author={Claude C. Schulman and Erik Bastiaan Cornel and Vsevolod Matveev and Teuvo L J Tammela and J. Schraml and Henri Bensadoun and Wolfgang Warnack and Raj A Persad and Marek S. Salagierski and Francisco G{\'o}mez Veiga and Edwina S. Baskin-Bey and Beatr{\'i}z Franco L{\'o}pez and Bertrand Tombal},
  journal={European urology},
  year={2016},
  volume={69 4},
  pages={
          720-727
        }
}
BACKGROUND Intermittent androgen deprivation (IAD) has received increasing attention; however, the current literature is still limited, especially in nonmetastatic prostate cancer (PCa), and the relative efficacy and safety benefits of IAD versus continuous androgen deprivation (CAD) remain unclear. OBJECTIVE To add to the knowledge base regarding efficacy and potential benefits, including reduced side effects and improved quality of life (QoL), of IAD versus CAD in patients with… CONTINUE READING
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