Intermittent Hypercapnic Hypoxia Induced Protein Changes in the Piglet Hippocampus Identified by MALDI-TOF-MS

Abstract

Intermittent hypercapnic hypoxia (IHH) induces protein changes in the brainstem, but its effects on the hippocampus have not yet been studied. Using a proteomics-based approach, we tested the hypothesis that IHH up-regulates apoptotic promoters and down-regulates apoptotic inhibitors in the developing hippocampus. Male piglets aged 13–14 days were assigned… (More)
DOI: 10.1007/s11064-009-0021-x

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@article{Tang2009IntermittentHH, title={Intermittent Hypercapnic Hypoxia Induced Protein Changes in the Piglet Hippocampus Identified by MALDI-TOF-MS}, author={Samantha Tang and Rita Machaalani and Mohammad Abul Kashem and Izuru Matsumoto and Karen A Waters}, journal={Neurochemical Research}, year={2009}, volume={34}, pages={2215-2225} }