Intermingling versus clonal coherence during skeletal muscle development: mosaicism in eGFP/nLacZ-labeled mouse chimeras.

Abstract

To study the relative contributions of clonal coherence vs. myoblast intermingling to the formation of mammalian skeletal muscles, enhanced green fluorescent protein (eGFP) and nLacZ labels were used to analyze neonatal and adult mouse embryo aggregation chimeras. The eGFP marker allowed us to estimate absolute levels of the eGFP transgenic parental… (More)

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