Intermedin 1-53 in central nervous system elevates arterial blood pressure in rats.

@article{Ren2006Intermedin1I,
  title={Intermedin 1-53 in central nervous system elevates arterial blood pressure in rats.},
  author={Yong-Sheng Ren and Jing-Hui Yang and Jing Jun Zhang and Chun-shui Pan and Jun Yang and Jing Zhao and Yong-zheng Pang and Chao-shu Tang and Yong-fen Qi},
  journal={Peptides},
  year={2006},
  volume={27 1},
  pages={74-9}
}
Intermedin (IMD) is a novel member of the calcitonin/calcitonin gene-related peptide (CGRP) family identified from human and other vertebrate tissues. Preprointermedin can generate various mature peptides by proteolytic cleavage. Amino acid sequence analysis showed cleavage sites located between two basic amino acids at Arg93-Arg94 resulting in the production of prepro-IMD(95-147), namely IMD(1-53). The present study was designed to determine the effects of the IMD(1-53) fragment in the central… CONTINUE READING
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