Intermediates in Endogenous Synthesis of C22:6ω3 and C20:4ω6 by Term and Preterm Infants


An alternative pathway of ω3 and ω6 fatty acid metabolism has been described in isolated rat hepatocytes and human fibroblasts. This alternative pathway, which is independent of Δ4 desaturation, involves elongation of C22:5ω3 and C22:4ω6 to C24 fatty acids,Δ6 desaturation of the C24 fatty acids and subsequent β oxidation of the desaturated products to C22:6… (More)
DOI: 10.1203/00006450-199702000-00005


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