63 Citations
Short- and Long-Term Memory in Drosophila Require cAMP Signaling in Distinct Neuron Types
- BiologyCurrent Biology
- 2009
The Making of Long-Lasting Memories: A Fruit Fly Perspective
- BiologyFrontiers in Behavioral Neuroscience
- 2021
Recent literature regarding how the formation of memories induces a rapid, extensive and, in many cases, transient wave of transcriptional activity is reviewed.
The Contribution of Spatial and Temporal Molecular Networks in the Induction of Long-term Memory and Its Underlying Synaptic Plasticity
- BiologyAIMS neuroscience
- 2016
It is proposed that evaluating how cells integrate and interpret these concurrent and interacting molecular networks has the potential to significantly advance the understanding of the mechanisms underlying learning and memory formation.
Transcriptional regulation of long-term potentiation
- Biologyneurogenetics
- 2016
Identification of all the proteins and non-coding RNA transcripts expressed during LTP may provide greater insight into the molecular mechanisms involved in learning and memory formation.
Pattern and predictability in memory formation: From molecular mechanisms to clinical relevance
- Psychology, BiologyNeurobiology of Learning and Memory
- 2013
Massed Training-Induced Intermediate-Term Operant Memory in Aplysia Requires Protein Synthesis and Multiple Persistent Kinase Cascades
- BiologyThe Journal of Neuroscience
- 2012
It is found that massed LFI training resulted in temporally distinct protein synthesis-dependent memory evident 4–6 h after training, and sustained MAPK phosphorylation was dependent upon protein synthesis, but not PKA or PKC activity.
Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition
- Biology, PsychologyBehavioural Brain Research
- 2009
Latent memory facilitates relearning through molecular signaling mechanisms that are distinct from original learning
- Biology, PsychologyNeurobiology of Learning and Memory
- 2015
Parallel processing of olfactory memories in Drosophila
- Biology, PsychologyFly
- 2010
Using an aversive olfactory conditioning task in Drosophila, it is found that cAMP signaling in different neuron cell types is sufficient to support short or long-term memory independently.
The role of protein synthesis in memory consolidation: Progress amid decades of debate
- BiologyNeurobiology of Learning and Memory
- 2008
References
SHOWING 1-10 OF 73 REFERENCES
A novel intermediate stage in the transition between short- and long-term facilitation in the sensory to motor neuron synapse of aplysia
- BiologyNeuron
- 1995
Intermediate-Term Memory for Site-Specific Sensitization in Aplysia Is Maintained by Persistent Activation of Protein Kinase C
- BiologyThe Journal of Neuroscience
- 2004
It is shown that a single tail shock can also induce ITM that is expressed selectively at the trained site (site-specific ITM), which is phenotypically similar to the form of ITM induced by repeated trials, but the mechanisms by which site- specific ITM is induced and maintained are distinct.
Dynamics of Induction and Expression of Long-Term Synaptic Facilitation in Aplysia
- BiologyThe Journal of Neuroscience
- 1996
The hypothesis that LTF is not a simple elaboration of STF is supported, raising the possibility that STF, ITF, and LTF may reflect components of different memory phases in the intact animal.
Molecular Mechanisms Underlying a Unique Intermediate Phase of Memory in Aplysia
- Biology, PsychologyNeuron
- 2001
Interaction between amount and pattern of training in the induction of intermediate- and long-term memory for sensitization in aplysia.
- Biology, PsychologyLearning & memory
- 2002
The results indicate that in addition to three identified phases of memory for sensitization--STM, ITM, and LTM--a unique temporal profile of memory, E-ITM, is revealed by varying either the amount or pattern of training.
Dynamic memory networks: dissecting molecular mechanisms underlying associative memory in the temporal domain.
- BiologyCellular and molecular life sciences : CMLS
- 2006
The temporal features of molecular processes in learning and memory formation are focused on, recent knowledge is summarized, current knowledge is presented and an outlook on future developments is presented.
A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia.
- BiologyScience
- 1986
The results parallel those for behavioral performance in vertebrates and indicate that the critical time window characteristic of the requirement for macromolecular synthesis in long-term heterosynaptic facilitation is not a property of complex circuitry, but an intrinsic characteristic of specific nerve cells and synaptic connections involved in the long- term storage of information.
Induction of long-term facilitation in Aplysia sensory neurons by local application of serotonin to remote synapses.
- BiologyProceedings of the National Academy of Sciences of the United States of America
- 1993
This work has explored a set of remote, peripheral terminals of siphon sensory cells, which are approximately 3 cm from the sensory cell body in the abdominal ganglion, and found that these remote synapses, like the proximal synapses previously studied in dissociated cell culture, can exhibit long-term facilitation 24 hr after cell-wide serotonin application.