Intermediate filaments of the lung

  title={Intermediate filaments of the lung},
  author={Hayan Yi and Nam-On Ku},
  journal={Histochemistry and Cell Biology},
Intermediate filaments (IF), a subfamily of the cytoskeletal filaments, provide structural support to cells. Human diseases related to mutations in IF proteins in which their tissue-specific expression is reflected have been found in a broad range of patients. The properties of identified IF mutants are well-studied in vitro in cultured cells and in vivo using transgenic mice expressing IF mutants. However, the association of IF proteins with diseases of the lung is not fully studied yet… CONTINUE READING