Intermediate filaments mediate cytoskeletal crosstalk

  title={Intermediate filaments mediate cytoskeletal crosstalk},
  author={Lynne Chang and R. Goldman},
  journal={Nature Reviews Molecular Cell Biology},
  • Lynne Chang, R. Goldman
  • Published 2004
  • Biology, Medicine
  • Nature Reviews Molecular Cell Biology
  • Intermediate filaments, actin-containing microfilaments and microtubules are the three main cytoskeletal systems of vertebrate and many invertebrate cells. Although these systems are composed of distinctly different proteins, they are in constant and intimate communication with one another. Understanding the molecular basis of this cytoskeletal crosstalk is essential for determining the mechanisms that underlie many cell-biological phenomena. Recent studies have revealed that intermediate… CONTINUE READING
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