Intermediate filaments in cell migration and invasion: the unusual suspects.

@article{Leduc2015IntermediateFI,
  title={Intermediate filaments in cell migration and invasion: the unusual suspects.},
  author={C{\'e}cile Leduc and Sandrine Etienne-Manneville},
  journal={Current opinion in cell biology},
  year={2015},
  volume={32},
  pages={102-12}
}
Cell migration is a multistep process which relies on the coordination of cytoskeletal structures in space and time. While the roles of actin and microtubules have been investigated in great details, the lack of inhibitors and visualizing tools and the large number of proteins forming intermediate filaments (IFs) have delayed the characterization of IF functions during migration. However, a large body of evidence has progressively pointed to changes in IF composition as an important parameter… CONTINUE READING