Intermediate filaments in alpha-keratins.

  title={Intermediate filaments in alpha-keratins.},
  author={R. D. Bruce Fraser and T. P. Macrae and David A Parry and E Suzuki},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={83 5},
Previous x-ray diffraction studies on the alpha-keratins of hair and wool have revealed that the intermediate filaments (IF) have a helical structure rendered imperfect by a precisely defined dislocation. It has also been possible to deduce a surface lattice for the IF and to determine the number of IF molecules associated with each lattice point. In this work this information is combined with data on the ionic interactions between the coiled-coil rope segments of the IF molecules to provide a… CONTINUE READING
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