Intermediate filaments and stress.

  title={Intermediate filaments and stress.},
  author={Milos Pekny and E. Birgitte Lane},
  journal={Experimental cell research},
  volume={313 10},
Before we can explain why so many closely related intermediate filament genes have evolved in vertebrates, while maintaining such dramatically tissue specific expression, we need to understand their function. The best evidence for intermediate filament function comes from observing the consequences of mutation and mis-expression, primarily in human tissues. Mostly these observations suggest that intermediate filaments are important in allowing individual cells, the tissues and whole organs to… CONTINUE READING

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