• Biology, Medicine
• Published in
  The Journal of Biological…
  2015
• DOI:10.1074/jbc.R115.640359

Intermediate Filaments Play a Pivotal Role in Regulating Cell Architecture and Function*

@article{Lowery2015IntermediateFP,
  title={Intermediate Filaments Play a Pivotal Role in Regulating Cell Architecture and Function*},
  author={Jason Lowery and Edward R. Kuczmarski and Harald Herrmann and Robert D Goldman},
  journal={The Journal of Biological Chemistry},
  year={2015},
  volume={290},
  pages={17145 - 17153}
}

• Jason Lowery, Edward R. Kuczmarski, +1 author Robert D Goldman

Intermediate filaments (IFs) are composed of one or more members of a large family of cytoskeletal proteins, whose expression is cell- and tissue type-specific. Their importance in regulating the physiological properties of cells is becoming widely recognized in functions ranging from cell motility to signal transduction. IF proteins assemble into nanoscale biopolymers with unique strain-hardening properties that are related to their roles in regulating the mechanical integrity of cells… CONTINUE READING

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