Interlocking Transcriptional Feedback Loops Control White-Opaque Switching in Candida albicans

@article{Zordan2007InterlockingTF,
  title={Interlocking Transcriptional Feedback Loops Control White-Opaque Switching in Candida albicans},
  author={Rebecca E. Zordan and Mathew G. Miller and David J. Galgoczy and Brian B. Tuch and Alexander Johnson},
  journal={PLoS Biology},
  year={2007},
  volume={5},
  pages={189 - 197}
}
The human pathogen Candida albicans can assume either of two distinct cell types, designated "white" and "opaque." Each cell type is maintained for many generations; switching between them is rare and stochastic, and occurs without any known changes in the nucleotide sequence of the genome. The two cell types differ dramatically in cell shape, colony… CONTINUE READING
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